The Proteomics division of the Laboratory for Molecular Biology and Cytometry Research is committed to providing the highest quality services related to proteomic analysis, specifically biomolecule mass spectrometry. The instrumentation available for mass spectrometry services includes an ABSciex QSTAR Elite hybrid quadrupole/TOF mass spectrometer, a Bruker-Daltonics HCT Ultra ion trap mass spectrometer, a Bruker Daltonics – Ultraflex-2 MALDI-TOF, and a Waters Synapt G2-S High Definition mass spectrometers. Several of our mass spectrometers are coupled to HPLC instruments which allows us to provide additional applications to our researchers. The QStar and the Bruker HCT ion trap are paired to 1D LC systems (Dionex Ultimate 3000 and Michrom Paradigm, respectively) while the Waters Synapt is paired to a 2D UPLC (nanoAcquity) in order to allow processing of more complex proteomic type samples.
Services provided by our facility include:
- High resolution molecular weight determination
- Large biomolecular mass measurements
- LC-UV-MS analysis (qualitative or quantitative)
- Protein identification by proteolytic digest (in-gel or in solution)
- nano LC-MSMS and database search
- Peptide sequencing
- Complex proteomics analysis
If you have any additional questions, please email the lab group (Lmbcr_help@ouhsc.edu) or contact Dr. Virginie Sjoelund.
To speak with someone in person, please feel free to call the main facility number at (405) 271-2337 to schedule an appointment during normal operating hours.
Our Office Hours are Monday through Friday: 8:00am to 5:00pm
Sample Drop Off is available Monday through Friday: 8:30am to 4:30pm
Note: All samples dropped off for proteomic analysis or for protein identification on a Friday won't be processed until Monday.
PUBLICATION ACKNOWLEDGEMENT: If research supported by this facility results in presentations or publication, we would really appreciate if you acknowledge this support by including the following in your presentation or publication(s):
We thank the Laboratory for Molecular Biology and Cytometry Research at OUHSC for the use of the Core Facility which provided __________ service.